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KMID : 1201420100030010013
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Journal of Neurocritical Care
2010 Volume.3 No. 1 p.13 ~ p.16
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A Case of Cerebral Infarction Possibly Associated with Para-Phenylenediamine
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Park Min-Keun
Kwon Seok-Beom
Kim Ye-Rim
Kim Ji-Ae
Lee Mi-Jeong
Jang Yun-Jung
Hong Seong-Sook
Kang Suk-Yun
Jung San
Hwang Sung-Hee
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Abstract
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Background: Permanent hair dyes are most commonly based on para-phenylenediamine (PPD). Adverse effects of cutaneous PPD intoxication are various from contact dermatitis to severe anaphylaxis. On the contrary, there was no report of PPD induced cerebrovascular disease.
Case Report: A 55-year-old diabetic man was adimitted to an intensive care unit because of left visual field defect and left side weakness 2 days after hair dye exposure. He had mild periorbital and facial edema. Neurological examination revealed left homonymous hemianopsia and left hemiparesis (MRC grade IV). Laboratory studies showed a high serum glucose, elevated serum osmolarity and serum creatinine. Diffusion weighted imaging revealed multiple high signal intensities in the right MCA and PCA territories. He was patch-tested for PPD, which was positive.
Conclusion: To our knowledge, this case is the first report of cerebral infarction developed after the exposure of PPD in a compromised diabetic patient.
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KEYWORD
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Cerebral infarction, Para-phenylenediamine, Hair dyes
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